RAB3B and PIGR

Number of citations of the paper that reports this interaction (PubMedID 11832247)
29

Data Source:
HPRD (in vitro, in vivo)

		RAB3B	PIGR
Description		RAB3B, member RAS oncogene family	polymeric immunoglobulin receptor
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GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Secretory Granule Cytoplasmic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding Myosin V Binding	Polymeric Immunoglobulin Receptor Activity
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering Neutrophil Degranulation
Pathways		RAB geranylgeranylation	Neutrophil degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)
Interacting Genes		13 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RIMS2 RPH3A RPH3AL SMAD1 SMAD4 TGFBR1	4 interacting genes: AP1M1 CCL5 CD79A RAB3B
Entrez ID		5865	5284
HPRD ID		01540	01436
Ensembl ID		ENSG00000169213	ENSG00000162896
Uniprot IDs		P20337	P01833
PDB IDs		3DZ8	1XED 2OCW 3CHN 3CM9 5D4K
Enriched GO Terms of Interacting Partners?
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