PIGR and AP1M1

Number of citations of the paper that reports this interaction (PubMedID 10809756)
27

Data Source:
HPRD (in vivo)

		PIGR	AP1M1
Description		polymeric immunoglobulin receptor	adaptor related protein complex 1 subunit mu 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Polymeric Immunoglobulin Receptor Activity	Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering Neutrophil Degranulation	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus
Pathways		Neutrophil degranulation	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)
Interacting Genes		4 interacting genes: AP1M1 CCL5 CD79A RAB3B	47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A
Entrez ID		5284	8907
HPRD ID		01436	04639
Ensembl ID		ENSG00000162896	ENSG00000072958
Uniprot IDs		P01833	A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5
PDB IDs		1XED 2OCW 3CHN 3CM9 5D4K
Enriched GO Terms of Interacting Partners?
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