NEUROD4 and GABRB1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NEUROD4	GABRB1
Description		neuronal differentiation 4	gamma-aminobutyric acid type A receptor subunit beta1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nuclear Envelope Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane GABA-ergic Synapse GABA-A Receptor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity	GABA-A Receptor Activity Ligand-gated Ion Channel Activity GABA-gated Chloride Ion Channel Activity GABA Receptor Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Neuron Migration Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Neuroblast Proliferation Glial Cell Differentiation Amacrine Cell Differentiation Cell Fate Commitment Positive Regulation Of Cell Differentiation Neuron Development	Ion Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Response To Toxic Substance Central Nervous System Neuron Development Response To Progesterone Ion Transmembrane Transport Regulation Of Membrane Potential Ovulation Cycle Nervous System Process Regulation Of Postsynaptic Membrane Potential Cellular Response To Histamine Chloride Transmembrane Transport
Pathways			Signaling by ERBB4 GABA receptor activation GABA receptor activation
Drugs			Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Topiramate Etomidate Talbutal Pentobarbital Olanzapine Clobazam Meprobamate Eszopiclone Alprazolam Lindane Metharbital Chlordiazepoxide Amoxapine Adinazolam Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Triazolam Triazolam Ethanol Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Flumazenil Estazolam Estazolam Sevoflurane Glutethimide Gamma Hydroxybutyric Acid Bromazepam Clotiazepam Fludiazepam Ketazolam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Stiripentol Thiocolchicoside
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Lead levels ( 26025379) Severe influenza A (H1N1) infection ( 26379185) Spontaneous preterm birth without premature rupture of membranes ( 31194736)	Adventurousness ( 30643258) Cervical cancer ( 28806749) Familial squamous cell lung carcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Major depressive disorder ( 29317602) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		3 interacting genes: GABRB1 LRRN2 RNF41	7 interacting genes: AKAP5 ARFGEF2 C1QBP NEUROD4 NOD1 PIK3CA UBQLN1
Entrez ID		58158	2560
HPRD ID		14826	15924
Ensembl ID		ENSG00000123307	ENSG00000163288
Uniprot IDs		Q8IW56 Q9HD90	P18505 X5DNL6
PDB IDs
Enriched GO Terms of Interacting Partners?
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