GABRB1 and NEUROD4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GABRB1	NEUROD4
Description		gamma-aminobutyric acid type A receptor subunit beta1	neuronal differentiation 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane GABA-ergic Synapse GABA-A Receptor Complex	Nuclear Chromatin
	Molecular Function	GABA-A Receptor Activity Ligand-gated Ion Channel Activity GABA-gated Chloride Ion Channel Activity GABA Receptor Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity
	Biological Process	Ion Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Response To Toxic Substance Central Nervous System Neuron Development Response To Progesterone Ion Transmembrane Transport Regulation Of Membrane Potential Ovulation Cycle Nervous System Process Regulation Of Postsynaptic Membrane Potential Cellular Response To Histamine Chloride Transmembrane Transport	Neuron Migration Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Neuroblast Proliferation Glial Cell Differentiation Amacrine Cell Differentiation Cell Fate Commitment Positive Regulation Of Cell Differentiation Neuron Development
Pathways		Signaling by ERBB4 GABA receptor activation GABA receptor activation
Drugs		Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Topiramate Etomidate Talbutal Pentobarbital Olanzapine Clobazam Meprobamate Eszopiclone Alprazolam Lindane Metharbital Chlordiazepoxide Amoxapine Adinazolam Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Triazolam Triazolam Ethanol Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Flumazenil Estazolam Estazolam Sevoflurane Glutethimide Gamma Hydroxybutyric Acid Bromazepam Clotiazepam Fludiazepam Ketazolam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Stiripentol Thiocolchicoside
Diseases
GWAS		Adventurousness ( 30643258) Cervical cancer ( 28806749) Familial squamous cell lung carcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Major depressive disorder ( 29317602) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Asthma (childhood onset) ( 31036433) Lead levels ( 26025379) Severe influenza A (H1N1) infection ( 26379185) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		7 interacting genes: AKAP5 ARFGEF2 C1QBP NEUROD4 NOD1 PIK3CA UBQLN1	3 interacting genes: GABRB1 LRRN2 RNF41
Entrez ID		2560	58158
HPRD ID		15924	14826
Ensembl ID		ENSG00000163288	ENSG00000123307
Uniprot IDs		P18505 X5DNL6	Q8IW56 Q9HD90
PDB IDs
Enriched GO Terms of Interacting Partners?
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