MATR3 and SNRNP200

Number of citations of the paper that reports this interaction (PubMedID 25849387)
8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MATR3	SNRNP200
Description		matrin 3	small nuclear ribonucleoprotein U5 subunit 200
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Innate Immune Response	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)	Retinitis pigmentosa (RP)
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		18 interacting genes: AIMP2 AKTIP CALM1 EGFR ERG GFI1B HNRNPK LMNA PCBP1 PTBP2 RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF6 TTF2 UBE2I	29 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B DHX38 ECT2 EFTUD2 ERG GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PRPF8 RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 UBE2I USP19 YWHAB YWHAG
Entrez ID		9782	23020
HPRD ID		05270	03391
Ensembl ID		ENSG00000015479	ENSG00000144028
Uniprot IDs		A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1	O75643
PDB IDs			2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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