PLEKHA4 and EEF1G

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHA4	EEF1G
Description		pleckstrin homology domain containing A4	eukaryotic translation elongation factor 1 gamma
Image
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Translation Elongation Factor Activity Protein Binding Cadherin Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Biological_process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway	Translational Elongation Response To Virus
Pathways		Synthesis of PIPs at the plasma membrane	Eukaryotic Translation Elongation
Drugs		Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		7 interacting genes: ABL1 ATP5MG CCNG1 EEF1G KAT5 LRIF1 SETDB1	88 interacting genes: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LZTS1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		57664	1937
HPRD ID		09683	11745
Ensembl ID		ENSG00000105559	ENSG00000254772
Uniprot IDs		Q9H4M7	P26641 Q53YD7
PDB IDs		1UPQ 1UPR	1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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