MIB1 and GABARAP

Number of citations of the paper that reports this interaction (PubMedID 28712572)
20

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MIB1	GABARAP
Description		mindbomb E3 ubiquitin protein ligase 1	GABA type A receptor-associated protein
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Autophagosome Maturation
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Severe progression in rheumatoid arthritis ( 29065906)
Interacting Genes		20 interacting genes: AZI2 BLM CABLES1 CEP131 CHST9 DAB2 DAPK1 EPB41L4A GABARAP JAG1 RMC1 SNX5 TBK1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W	51 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 NBR1 NEDD4 NSF OPTN PCM1 PGS1 PKP4 RB1CC1 RETREG1 SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TUBB3 ULK1 ULK2 VPS28
Entrez ID		57534	11337
HPRD ID		06660	05496
Ensembl ID		ENSG00000101752	ENSG00000170296
Uniprot IDs		Q86YT6	O95166 Q6IAW1
PDB IDs		4TSE 4XI6 4XI7 4XIB	1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO
Enriched GO Terms of Interacting Partners?
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