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NDRG2 and TRIM32
Number of citations of the paper that reports this interaction (PubMedID
25701873
)
12
Data Source:
BioGRID
(enzymatic study)
NDRG2
TRIM32
Description
NDRG family member 2
tripartite motif containing 32
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Cytosol
Growth Cone
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell
Nucleus
Cytoplasm
Cytosol
Striated Muscle Myosin Thick Filament
Molecular Function
Molecular_function
Protein Binding
Transcription Coactivator Activity
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Myosin Binding
Tat Protein Binding
Translation Initiation Factor Binding
Identical Protein Binding
Ubiquitin Binding
Protein Self-association
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Cytokine Production
Signal Transduction
Regulation Of Vascular Endothelial Growth Factor Production
Wnt Signaling Pathway
Substantia Nigra Development
Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of ERK1 And ERK2 Cascade
Regulation Of Platelet-derived Growth Factor Production
Protein Polyubiquitination
Tissue Homeostasis
Ubiquitin-dependent Protein Catabolic Process
Actin Ubiquitination
Response To UV
Protein Ubiquitination
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Regulation Of Type I Interferon Production
Negative Regulation Of Viral Transcription
Response To Tumor Necrosis Factor
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Fat Cell Differentiation
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis
Muscle Cell Cellular Homeostasis
Negative Regulation Of Fibroblast Proliferation
Positive Regulation Of Neurogenesis
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Striated Muscle Cell Differentiation
Axon Development
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Interleukin-17-mediated Signaling Pathway
Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production
Positive Regulation Of Cell Motility
Pathways
Regulation of innate immune responses to cytosolic DNA
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Bardet-Biedl syndrome (BBS)
GWAS
Heart rate response to exercise (
29769521
)
Hip circumference adjusted for BMI (
28552196
)
Metabolite levels (small molecules and protein measures) (
27005778
)
Resting heart rate (
27798624
)
Estimated glomerular filtration rate (
31015462
)
Interacting Genes
6 interacting genes:
ATP1B1
CLN8
CTDP1
MOB2
RABAC1
TRIM32
41 interacting genes:
ABI2
ATXN1
CLIP4
GLIS2
HSPA4
IQCB1
IRAK1
KCTD9
MID2
MYCN
NDRG2
PDE9A
PIAS3
PIAS4
PTCD2
PTPN11
RABAC1
RNF208
RNF41
SCGB1A1
SDCBP
STING1
SYT6
TOP1
TRIM23
TRIM27
TRIM5
TRIM72
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBQLN1
UBQLN4
VPS11
XIAP
Entrez ID
57447
22954
HPRD ID
17630
03797
Ensembl ID
ENSG00000165795
ENSG00000119401
Uniprot IDs
Q9UN36
A0A024R843
Q13049
PDB IDs
2XMQ
2XMR
2XMS
2CT2
5FEY
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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