JPH3 and BGN

Number of citations of the paper that reports this interaction (PubMedID 11145944)
9

Data Source:
BioGRID (pull down)

		JPH3	BGN
Description		junctophilin 3	biglycan
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Junctional Membrane Complex	Extracellular Region Extracellular Space Golgi Lumen Cell Surface Transport Vesicle Extracellular Matrix Sarcolemma Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Molecular_function	Extracellular Matrix Structural Constituent Protein Binding Glycosaminoglycan Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance Extracellular Matrix Binding
	Biological Process	Learning Memory Exploration Behavior Locomotion Regulation Of Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Neuromuscular Process Controlling Balance Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Transport Into Cytosol	Blood Vessel Remodeling Biological_process Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Bone Development Articular Cartilage Development
Pathways			A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation ECM proteoglycans ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases		Core neuroacanthocytosis syndromes, including: Chorea-acanthocytosis (ChAc); McLeod syndrome (MLS); Huntington's disease-like 2 (HDL2); Pantothenate kinase associated neurodegeneration (PKAN)
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Height ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ischemic stroke ( 29531354) Late-onset Alzheimer's disease ( 27770636) Migraine ( 27182965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio in smoking ( 30068317) Small vessel stroke ( 27997041) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		3 interacting genes: BGN PPP1CA SMAD3	17 interacting genes: - APOB APP BMP4 CCN4 COL1A1 COL1A2 COL2A1 COL4A2 DAG1 ELN HSPB2 JPH3 MFAP2 PLA2G1B TGFB1 TNF
Entrez ID		57338	633
HPRD ID		05589	02359
Ensembl ID		ENSG00000154118	ENSG00000182492
Uniprot IDs		B4DIC1 F8W9A3 Q8WXH2 Q96HD8	B4DNL4 P21810
PDB IDs
Enriched GO Terms of Interacting Partners?
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