TMEM159 and GAD2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TMEM159	GAD2
Description		transmembrane protein 159	glutamate decarboxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Cytosol Plasma Membrane Cell Junction Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Protein Binding	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding
	Biological Process		Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Neurotransmitter Biosynthetic Process Response To Drug
Pathways			GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal Phosphate Glutamic Acid
Diseases
GWAS			Lean body mass ( 28552196)
Interacting Genes		5 interacting genes: CACFD1 COQ8A GAD2 S100B ZNF391	9 interacting genes: AGTRAP ARL6IP1 CMTM5 F10 GAD1 MAL2 PRKACA PRKCE TMEM159
Entrez ID		57146	2572
HPRD ID		17428	11817
Ensembl ID		ENSG00000011638	ENSG00000136750
Uniprot IDs		I3L288 I3NI23 Q96B96	Q05329 Q5VZ30
PDB IDs			1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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