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GAD2

Description glutamate decarboxylase 2
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Cytosol
  • Plasma Membrane
  • Cell Junction
  • Axon
  • Synaptic Vesicle Membrane
  • Anchored Component Of Membrane
  • Presynaptic Membrane
  • Perinuclear Region Of Cytoplasm
  • Inhibitory Synapse
  • Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Molecular Function
  • Glutamate Decarboxylase Activity
  • Protein Binding
  • Glutamate Binding
  • Pyridoxal Phosphate Binding
  • Protein-containing Complex Binding
Biological Process
  • Glutamate Decarboxylation To Succinate
  • Chemical Synaptic Transmission
  • Neurotransmitter Secretion
  • Neurotransmitter Biosynthetic Process
  • Response To Drug
Pathways
  • GABA synthesis
  • GABA synthesis, release, reuptake and degradation
  • MECP2 regulates transcription of genes involved in GABA signaling
Drugs
  • Pyridoxal Phosphate
  • Glutamic Acid
Diseases
GWAS
  • Lean body mass ( 28552196)
Interacting Genes 9 interacting genes: AGTRAP ARL6IP1 CMTM5 F10 GAD1 MAL2 PRKACA PRKCE TMEM159
Entrez ID 2572
HPRD ID 11817
Ensembl ID ENSG00000136750
Uniprot IDs Q05329 Q5VZ30
PDB IDs 1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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