ERO1B and P4HB

Number of citations of the paper that reports this interaction (PubMedID 11847130)
60

Data Source:
HPRD (in vivo)

		ERO1B	P4HB
Description		endoplasmic reticulum oxidoreductase 1 beta	prolyl 4-hydroxylase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Extracellular Region Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Cytoskeleton Focal Adhesion External Side Of Plasma Membrane Procollagen-proline 4-dioxygenase Complex Lamellipodium Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Unfolded Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Actin Binding Procollagen-proline 4-dioxygenase Activity Integrin Binding Protein Binding Peptide Disulfide Oxidoreductase Activity Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Protein Folding Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Insulin Processing Extracellular Matrix Organization Protein Folding In Endoplasmic Reticulum Glucose Homeostasis Cell Redox Homeostasis Oxidation-reduction Process	Protein Folding Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Chylomicron Assembly Very-low-density Lipoprotein Particle Assembly Response To Endoplasmic Reticulum Stress Interleukin-12-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Cell Redox Homeostasis Positive Regulation Of Cell Adhesion Positive Regulation Of Viral Entry Into Host Cell Oxidation-reduction Process Cellular Response To Hypoxia Cellular Response To Interleukin-7 Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Insulin processing	Collagen biosynthesis and modifying enzymes Detoxification of Reactive Oxygen Species Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Hedgehog ligand biogenesis VLDL assembly Post-translational protein phosphorylation Chylomicron assembly Interleukin-12 signaling Interleukin-23 signaling
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione Flavin adenine dinucleotide	Zinc Ribostamycin Copper
Diseases
GWAS
Interacting Genes		10 interacting genes: ACTL6A BRCA1 CNRIP1 ERP44 GNG4 HMGCS2 P4HB PARVA PYGM TARBP1	22 interacting genes: CD1D COL10A1 COL1A1 COL1A2 CSNK2A2 EIF2S1 ERO1A ERO1B ESR1 FEZ1 HNRNPD ITGB3 LGALS9 LINC00839 P4HA2 P4HA3 PRNP PTN TG UBQLN1 VWF YWHAG
Entrez ID		56605	5034
HPRD ID		13279	07181
Ensembl ID		ENSG00000086619	ENSG00000185624
Uniprot IDs		Q86YB8	A0A024R8S5 P07237
PDB IDs			1BJX 1MEK 1X5C 2BJX 2K18 3BJ5 3UEM 4EKZ 4EL1 4JU5 6I7S
Enriched GO Terms of Interacting Partners?
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