PSAP and CD1B

Number of citations of the paper that reports this interaction (PubMedID 14716313)
60

Data Source:
HPRD (in vitro)

		PSAP	CD1B
Description		prosaposin	CD1b molecule
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Aggresome Azurophil Granule Membrane Lysosomal Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Space Lysosomal Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding Protease Binding Beta-galactosidase Activity Protein Binding Phospholipid Binding Enzyme Activator Activity Lipid Binding Lipid Antigen Binding Protein Homodimerization Activity Ganglioside GM1 Binding Ganglioside GM2 Binding Ganglioside GM3 Binding Ganglioside GT1b Binding Ganglioside GP1c Binding	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	NK T Cell Differentiation Platelet Degranulation Corneocyte Development Glucosylceramide Metabolic Process Galactosylceramide Catabolic Process Glycosphingolipid Metabolic Process Lipid Transport Intracellular Protein Transport Lysosomal Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Sound Protein Secretion Gene Expression Regulation Of Autophagy Regulation Of Lipid Metabolic Process Antigen Processing And Presentation Cerebellar Purkinje Cell Differentiation Myelination Neutrophil Degranulation Positive Regulation Of MAPK Cascade Neuromuscular Process Controlling Balance Positive Regulation Of Hydrolase Activity Micturition Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Inclusion Body Assembly Cellular Response To Organic Substance Cochlea Development Walking Behavior Negative Regulation Of Hydrogen Peroxide-induced Cell Death Cornified Envelope Assembly Lysosomal Protein Catabolic Process Ganglioside GM1 Transport To Membrane	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Immune Response
Pathways		Platelet degranulation Glycosphingolipid metabolism Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases		Krabbe disease; Globoid cell leukodystrophy Metachromatic leukodystrophy (MLD) Gaucher disease
GWAS		Asthma (childhood onset) ( 23829686) Blood protein levels ( 30072576) Seasonality and depression ( 30217971)
Interacting Genes		18 interacting genes: BACE1 BRCA1 CD1B CELSR1 COPS6 CPEB2 CTSD ERBB2 GBA MAFF NLGN3 PRAG1 SMAD2 SMAD9 TOMM70 UBE3A USP4 ZBED1	3 interacting genes: B2M HSBP1 PSAP
Entrez ID		5660	910
HPRD ID		01460	01775
Ensembl ID		ENSG00000197746	ENSG00000158485
Uniprot IDs		A0A024QZQ2 P07602	P29016
PDB IDs		1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ 4UEX 4V2O	1GZP 1GZQ 1UQS 2H26 3OV6 3T8X 4ONO 5C9J 5L2J 5L2K 5WKE 5WKG 5WKI 5WL1 6CUG 6D64
Enriched GO Terms of Interacting Partners?
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