PSAP and MAFF

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PSAP	MAFF
Description		prosaposin	MAF bZIP transcription factor F
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Aggresome Azurophil Granule Membrane Lysosomal Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion
	Molecular Function	G Protein-coupled Receptor Binding Protease Binding Beta-galactosidase Activity Protein Binding Phospholipid Binding Enzyme Activator Activity Lipid Binding Lipid Antigen Binding Protein Homodimerization Activity Ganglioside GM1 Binding Ganglioside GM2 Binding Ganglioside GM3 Binding Ganglioside GT1b Binding Ganglioside GP1c Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	NK T Cell Differentiation Platelet Degranulation Corneocyte Development Glucosylceramide Metabolic Process Galactosylceramide Catabolic Process Glycosphingolipid Metabolic Process Lipid Transport Intracellular Protein Transport Lysosomal Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Sound Protein Secretion Gene Expression Regulation Of Autophagy Regulation Of Lipid Metabolic Process Antigen Processing And Presentation Cerebellar Purkinje Cell Differentiation Myelination Neutrophil Degranulation Positive Regulation Of MAPK Cascade Neuromuscular Process Controlling Balance Positive Regulation Of Hydrolase Activity Micturition Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Inclusion Body Assembly Cellular Response To Organic Substance Cochlea Development Walking Behavior Negative Regulation Of Hydrogen Peroxide-induced Cell Death Cornified Envelope Assembly Lysosomal Protein Catabolic Process Ganglioside GM1 Transport To Membrane	In Utero Embryonic Development Transcription By RNA Polymerase II Parturition Blood Coagulation Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Platelet degranulation Glycosphingolipid metabolism Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation	Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs		Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases		Krabbe disease; Globoid cell leukodystrophy Metachromatic leukodystrophy (MLD) Gaucher disease
GWAS		Asthma (childhood onset) ( 23829686) Blood protein levels ( 30072576) Seasonality and depression ( 30217971)	Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)
Interacting Genes		18 interacting genes: BACE1 BRCA1 CD1B CELSR1 COPS6 CPEB2 CTSD ERBB2 GBA MAFF NLGN3 PRAG1 SMAD2 SMAD9 TOMM70 UBE3A USP4 ZBED1	22 interacting genes: ATF3 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFG MAFIP NFE2 NFE2L1 NFE2L2 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP SUN2
Entrez ID		5660	23764
HPRD ID		01460	05343
Ensembl ID		ENSG00000197746	ENSG00000185022
Uniprot IDs		A0A024QZQ2 P07602	Q9ULX9
PDB IDs		1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ 4UEX 4V2O
Enriched GO Terms of Interacting Partners?
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