ADAP2 and NCL

Number of citations of the paper that reports this interaction (PubMedID 18298663)
6

Data Source:
BioGRID (pull down)

		ADAP2	NCL
Description		ArfGAP with dual PH domains 2	nucleolin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Envelope Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Binding, Bridging Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding
	Biological Process	Heart Development Positive Regulation Of GTPase Activity Inositol Lipid-mediated Signaling	Angiogenesis Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Height ( 28552196) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252)	Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Height ( 31562340) Noise-induced hearing loss ( 26121033)
Interacting Genes		9 interacting genes: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA TUBB	53 interacting genes: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		55803	4691
HPRD ID		16357	01245
Ensembl ID		ENSG00000184060	ENSG00000115053
Uniprot IDs		Q2V6Q1 Q9NPF8	B3KM80 P19338
PDB IDs			2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?
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