VAC14 and ACSS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VAC14	ACSS1
Description		VAC14 component of PIKFYVE complex	acyl-CoA synthetase short chain family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex	Mitochondrial Matrix
	Molecular Function	Protein Binding Signaling Receptor Activity	Acetate-CoA Ligase Activity Protein Binding ATP Binding AMP Binding Propionate-CoA Ligase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity	Ethanol Oxidation Acetyl-CoA Biosynthetic Process Acetate Biosynthetic Process Acetyl-CoA Biosynthetic Process From Acetate Propionate Biosynthetic Process
Pathways		Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane	Ethanol oxidation
Drugs			Adenosine monophosphate ATP
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pulse pressure ( 28135244)	Bitter alcoholic beverage consumption ( 31046077) Cognitive performance ( 20125193) Lumbar spine bone mineral density (integral) ( 27476799)
Interacting Genes		53 interacting genes: ACSS1 APP ASB13 BCL2L1 BHLHE40 C11orf54 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK DDAH2 FNDC3B GALT GINS3 HNRNPLL JMJD7 KRTAP19-5 KRTAP19-7 KYAT1 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 NTAQ1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TP53BP1 ZCWPW1 ZNF34	1 interacting genes: VAC14
Entrez ID		55697	84532
HPRD ID		07660	12413
Ensembl ID		ENSG00000103043	ENSG00000154930
Uniprot IDs		Q08AM6	Q1RMZ4 Q9NUB1
PDB IDs			3GLR 3GLT 3GLU 4BVE 4BVF 4BVG 4C78 5Y4H 5YTK
Enriched GO Terms of Interacting Partners?
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