CHD7 and CTCF

Number of citations of the paper that reports this interaction (PubMedID 17603073)
11

Data Source:
BioGRID (unspecified method)

		CHD7	CTCF
Description		chromodomain helicase DNA binding protein 7	CCCTC-binding factor
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA Helicase Activity Chromatin Binding Protein Binding ATP Binding Promoter-specific Chromatin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Skeletal System Development In Utero Embryonic Development Blood Vessel Remodeling Heart Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Right Ventricular Compact Myocardium Morphogenesis Chromatin Remodeling Regulation Of Transcription, DNA-templated RRNA Processing Central Nervous System Development Adult Heart Development Sensory Perception Of Sound Adult Walking Behavior Blood Circulation Response To Bacterium Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cranial Nerve Development Olfactory Nerve Development Olfactory Bulb Development T Cell Differentiation Female Genitalia Development DNA Duplex Unwinding Embryonic Hindlimb Morphogenesis Aorta Morphogenesis Atrioventricular Canal Development Positive Regulation Of Multicellular Organism Growth Olfactory Behavior Inner Ear Morphogenesis Nose Development Positive Regulation Of Transcription By RNA Polymerase II Semicircular Canal Morphogenesis Genitalia Development Regulation Of Neurogenesis Cognition Retina Development In Camera-type Eye Regulation Of Growth Hormone Secretion Limb Development Face Development Innervation Cardiac Septum Morphogenesis Epithelium Development Secondary Palate Development	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Chromosome Segregation Negative Regulation Of Cell Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL) CHARGE syndrome
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Eosinophil counts ( 29403010 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Height ( 28552196) Lymphocyte percentage of white cells ( 27863252) Menopause (age at onset) ( 26414677) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244) Myeloid white cell count ( 27863252) Neutrophil count ( 29403010 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) Pulmonary function decline ( 22424883) Refractive error ( 23396134) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic sclerosis ( 31672989) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532) White blood cell count ( 29403010 27863252)	Elevated fasting plasma glucose ( 30004843) HDL cholesterol ( 19060911)
Interacting Genes		3 interacting genes: CHD8 CTCF GGH	19 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRB YBX1 ZMYM4
Entrez ID		55636	10664
HPRD ID		10595	05005
Ensembl ID		ENSG00000171316	ENSG00000102974
Uniprot IDs		Q6ZWF9 Q9P2D1	A0A2R8YFL0 P49711
PDB IDs		2CKC 2V0E 2V0F	1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL
Enriched GO Terms of Interacting Partners?
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