SHFL and PDE4DIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SHFL	PDE4DIP
Description		shiftless antiviral inhibitor of ribosomal frameshifting	phosphodiesterase 4D interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Viral Replication Complex	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	RNA Binding Protein Binding Ribosome Binding Sequence-specific MRNA Binding	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Translational Termination Response To Type I Interferon Response To Interferon-gamma Response To Type III Interferon Response To Interferon-beta Negative Regulation Of Viral Genome Replication Defense Response To Virus Viral Translational Frameshifting Negative Regulation Of Translational Frameshifting	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization
Pathways
Drugs
Diseases
GWAS			Capecitabine sensitivity ( 22864933)
Interacting Genes		34 interacting genes: ADAMTSL4 CADPS CCDC136 DRICH1 DTNBP1 ECSIT FBXL12 IKZF1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PDE4DIP SPRY2 SSX2IP TCF4 TERF1 TNS2 TRAF1	76 interacting genes: ADH1B AEN ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L EGR2 EIF4E2 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LMO4 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZDHHC17 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26
Entrez ID		55337	9659
HPRD ID		07747	10482
Ensembl ID		ENSG00000130813	ENSG00000178104
Uniprot IDs		Q9NUL5	A0A075B749 A0A087WYE4 Q5VU43
PDB IDs
Enriched GO Terms of Interacting Partners?
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