PSPC1 and NONO

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)
HPRD (in vivo, in vitro)

		PSPC1	NONO
Description		paraspeckle component 1	non-POU domain containing octamer binding
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding RNA Binding Protein Binding E-box Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Rhythmic Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		8 interacting genes: ESR1 KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4	42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1
Entrez ID		55269	4841
HPRD ID		10172	02098
Ensembl ID		ENSG00000121390	ENSG00000147140
Uniprot IDs		Q8WXF1	A0A0S2Z4Z9 Q15233
PDB IDs		3SDE 5IFN 5WPA	3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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