NONO and PSPC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)
HPRD (in vivo, in vitro)

		NONO	PSPC1
Description		non-POU domain containing octamer binding	paraspeckle component 1
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding	Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding RNA Binding Protein Binding E-box Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways
Drugs
Diseases
GWAS			Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1	8 interacting genes: ESR1 KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4
Entrez ID		4841	55269
HPRD ID		02098	10172
Ensembl ID		ENSG00000147140	ENSG00000121390
Uniprot IDs		A0A0S2Z4Z9 Q15233	Q8WXF1
PDB IDs		3SDE 5IFM	3SDE 5IFN 5WPA
Enriched GO Terms of Interacting Partners?
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