LRRC1 and CRMP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRRC1	CRMP1
Description		leucine rich repeat containing 1	collapsin response mediator protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cell-cell Junction Adherens Junction Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Synapse Postsynaptic Membrane Synaptic Membrane	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon
	Molecular Function		Dihydropyrimidinase Activity Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Filamin Binding Identical Protein Binding
	Biological Process	Embryo Development Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding
Pathways			CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)	Blood trace element (Zn levels) ( 23720494) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: APP CEP126 CRMP1 DLG1 DLG4 ERBIN	77 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24
Entrez ID		55227	1400
HPRD ID		06430	03913
Ensembl ID		ENSG00000137269	ENSG00000072832
Uniprot IDs		Q9BTT6	B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1
PDB IDs			4B3Z
Enriched GO Terms of Interacting Partners?
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