CRMP1 and NDUFV2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CRMP1	NDUFV2
Description		collapsin response mediator protein 1	NADH:ubiquinone oxidoreductase core subunit V2
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GO Annotations	Cellular Component	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Filamin Binding Identical Protein Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding	Mitochondrial Electron Transport, NADH To Ubiquinone Nervous System Development Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex I Assembly Cardiac Muscle Tissue Development
Pathways		CRMPs in Sema3A signaling	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Blood trace element (Zn levels) ( 23720494) Metabolite levels ( 23823483)	Cerebral amyloid deposition (PET imaging) ( 26252872) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		77 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24	3 interacting genes: CRMP1 KAT5 SP110
Entrez ID		1400	4729
HPRD ID		03913	02757
Ensembl ID		ENSG00000072832	ENSG00000178127
Uniprot IDs		B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1	P19404
PDB IDs		4B3Z	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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