MSL2 and APOBEC3B

Number of citations of the paper that reports this interaction (PubMedID 28608964)
15

Data Source:
BioGRID (enzymatic study)

		MSL2	APOBEC3B
Description		MSL complex subunit 2	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Image
GO Annotations	Cellular Component	Nucleoplasm MSL Complex	P-body Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Binding Cytidine Deaminase Activity Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Protein Ubiquitination Histone H4-K16 Acetylation	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways		HATs acetylate histones	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Alanine transaminase levels ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Blood urea nitrogen levels ( 31152163) C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Estimated glomerular filtration rate ( 31152163) Fibrinogen ( 23969696) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31217584) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Schizophrenia ( 28991256 25056061 29483656) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		13 interacting genes: APOBEC3B H2AC18 H2AC20 H2BC21 H3C14 H4C1 PAF1 TP53 TRIM8 UBE2D3 YWHAE YWHAG YWHAZ	1 interacting genes: MSL2
Entrez ID		55167	9582
HPRD ID		08550	06169
Ensembl ID		ENSG00000174579	ENSG00000179750
Uniprot IDs		Q9HCI7	Q9UH17
PDB IDs		4B7Y 4B86	2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM
Enriched GO Terms of Interacting Partners?
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