CDA and PTGER3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDA	PTGER3
Description		cytidine deaminase	prostaglandin E receptor 3
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Cell Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity	Prostaglandin E Receptor Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways		Neutrophil degranulation Pyrimidine salvage	Prostanoid ligand receptors G alpha (i) signalling events
Drugs		1-Beta-Ribofuranosyl-1,3-Diazepinone	Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Mean corpuscular volume ( 27863252) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Urinary metabolite levels in chronic kidney disease ( 31959995)	Dental caries (decayed, missing and filled teeth) ( 31533690) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)
Interacting Genes		10 interacting genes: FNDC11 KPNA2 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598	23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		978	5733
HPRD ID		11744	08906
Ensembl ID		ENSG00000158825	ENSG00000050628
Uniprot IDs		P32320	O00325 P43115
PDB IDs		1MQ0	6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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