PPM1G and GGCX

		PPM1G	GGCX
Description		protein phosphatase, Mg2+/Mn2+ dependent 1G	gamma-glutamyl carboxylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Gamma-glutamyl Carboxylase Activity Vitamin Binding
	Biological Process	Protein Dephosphorylation Cell Cycle Arrest Peptidyl-threonine Dephosphorylation	Cellular Protein Modification Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation
Pathways			Gamma-carboxylation of protein precursors Gamma-carboxylation of protein precursors
Drugs			Coagulation factor VIIa Recombinant Human Drotrecogin alfa Coagulation Factor IX (Recombinant) Glutamic Acid Menadione Phylloquinone Anisindione Coagulation Factor IX Human
Diseases			Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency Combined deficiency of vitamin K-dependent clotting factors (VKCFD)
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Prostate cancer ( 21743467)
Interacting Genes		11 interacting genes: FBXO38 GGCX GRIA3 H3-4 LRPAP1 MSL1 MTNR1B RPS6KA1 TERF1 TERF2 TERF2IP	14 interacting genes: ARFGAP1 ATP2C1 BGLAP CD8A F10 F2 F7 F9 FXN PDCD5 PPM1G PROC SRPK2 ST3GAL4
Entrez ID		5496	2677
HPRD ID		09237	00665
Ensembl ID		ENSG00000115241	ENSG00000115486
Uniprot IDs		O15355 Q6IAU5	P38435
PDB IDs
Enriched GO Terms of Interacting Partners?
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