GGCX

Description		gamma-glutamyl carboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Gamma-glutamyl Carboxylase Activity Vitamin Binding
	Biological Process	Cellular Protein Modification Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation
Pathways		Gamma-carboxylation of protein precursors Gamma-carboxylation of protein precursors
Drugs		Coagulation factor VIIa Recombinant Human Drotrecogin alfa Coagulation Factor IX (Recombinant) Glutamic Acid Menadione Phylloquinone Anisindione Coagulation Factor IX Human
Diseases		Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency Combined deficiency of vitamin K-dependent clotting factors (VKCFD)
GWAS		Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Prostate cancer ( 21743467)
Interacting Genes		14 interacting genes: ARFGAP1 ATP2C1 BGLAP CD8A F10 F2 F7 F9 FXN PDCD5 PPM1G PROC SRPK2 ST3GAL4
Entrez ID		2677
HPRD ID		00665
Ensembl ID		ENSG00000115486
Uniprot IDs		P38435
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?