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FBXL12 and MARCHF2

FBXL12

MARCHF2

Description F-box and leucine rich repeat protein 12 membrane associated ring-CH-type finger 2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • SCF Ubiquitin Ligase Complex
  • Lysosomal Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Endosome Membrane
  • Integral Component Of Membrane
  • Cytoplasmic Vesicle
Molecular Function
  • Protein Binding
  • Ubiquitin Protein Ligase Activity
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Zinc Ion Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Protein Polyubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
  • Regulation Of Cell Cycle
  • Endocytosis
  • Protein Ubiquitination
Pathways
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Pursuit maintenance gain ( 29064472)
Interacting Genes 22 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823 11 interacting genes: CDC34 CFTR ECSIT FATE1 FBXL12 KASH5 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H
Entrez ID 54850 51257
HPRD ID 12363 14361
Ensembl ID ENSG00000127452 ENSG00000099785
Uniprot IDs Q9NXK8 Q9P0N8
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025

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