MARCHF2 and STX6

Number of citations of the paper that reports this interaction (PubMedID 15689499)
32

Data Source:
HPRD (in vitro, in vivo)

		MARCHF2	STX6
Description		membrane associated ring-CH-type finger 2	syntaxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Endocytosis Protein Ubiquitination	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways			Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)
Interacting Genes		11 interacting genes: CDC34 CFTR ECSIT FATE1 FBXL12 KASH5 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H	15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18
Entrez ID		51257	10228
HPRD ID		14361	07231
Ensembl ID		ENSG00000099785	ENSG00000135823
Uniprot IDs		Q9P0N8	O43752
PDB IDs			2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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