TRPM7 and MBP

Number of citations of the paper that reports this interaction (PubMedID 14594813)
54

Data Source:
HPRD (in vitro)

		TRPM7	MBP
Description		transient receptor potential cation channel subfamily M member 7	myelin basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Cell Plasma Membrane Integral Component Of Membrane	Nucleus Plasma Membrane Cell Surface Protein-containing Complex Internode Region Of Axon Neuronal Cell Body Myelin Sheath Compact Myelin Synapse Cell Periphery
	Molecular Function	Actin Binding Protein Serine/threonine Kinase Activity Calcium Channel Activity ATP Binding Myosin Binding Metal Ion Binding	Protease Binding Protein Binding Calmodulin Binding Structural Constituent Of Myelin Sheath
	Biological Process	Cellular Magnesium Ion Homeostasis Calcium-dependent Cell-matrix Adhesion Actomyosin Structure Organization Protein Autophosphorylation Protein Tetramerization Necroptotic Process Calcium Ion Transmembrane Transport	MAPK Cascade Immune Response Chemical Synaptic Transmission Central Nervous System Development Sensory Perception Of Sound Axon Ensheathment Response To Toxic Substance Substantia Nigra Development Negative Regulation Of Heterotypic Cell-cell Adhesion Maintenance Of Permeability Of Blood-brain Barrier Myelination Membrane Organization Positive Regulation Of Chemokine (C-C Motif) Ligand 2 Secretion Positive Regulation Of Metalloendopeptidase Activity Positive Regulation Of Interleukin-6 Secretion
Pathways		TRP channels	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester 1,4-Dithiothreitol
Diseases
GWAS		Calcium levels ( 29403010) Chronic obstructive pulmonary disease ( 30804561) Household income (MTAG) ( 31844048) Pulse pressure ( 27841878) QT interval ( 24952745) Systolic blood pressure ( 27841878)	Age-related macular degeneration (geographic atrophy) ( 22705344) Blood osmolality (transformed sodium) ( 28360221) Depression in smokers ( 30219690) Erythrocyte cadmium concentration in never smokers ( 27005419) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Verbal declarative memory ( 25648963)
Interacting Genes		9 interacting genes: ANXA1 EEF2 H3-4 MBP PLCB1 PLCB2 PLCB3 PLCG1 TRPM6	72 interacting genes: ABL1 APTX ATN1 ATXN1 BMP2K CDK1 CDK12 CDK5 CDK7 CDK8 CDK9 CLK1 CTDSP1 DYRK1B HIPK2 HLA-DRA IKBKE ILK IRAK1 IRAK4 LIMK1 LIMK2 LRRK2 MAG MAP3K1 MAP3K3 MAP3K5 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPK8 MAPKAPK5 MELK MICU2 MKNK1 MMP7 NEK9 PAK1 PKN1 PLP1 PPP2R5C PRKACA PRKCA PRKCB PRKCD PRKCI PRKCZ PRKDC PRMT1 PRMT5 PTPRA RAN RPS6KA5 RTN4 SQSTM1 SRPK1 STK16 STK26 STK3 STK39 STK4 TBK1 TLK1 TLK2 TRAF6 TRPM7 TSSK6 ULK1
Entrez ID		54822	4155
HPRD ID		10418	01158
Ensembl ID		ENSG00000092439	ENSG00000197971
Uniprot IDs		A0A024R5V1 H0YLN8 Q96QT4	A0A024R384 P02686
PDB IDs			1BX2 1FV1 1HQR 1K2D 1QCL 1YMM 1ZGL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?