CTSA and LAMP2

Number of citations of the paper that reports this interaction (PubMedID 12505983)
49

Data Source:
HPRD (in vitro)

		CTSA	LAMP2
Description		cathepsin A	lysosomal associated membrane protein 2
Image
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Lumenal Side Of Lysosomal Membrane	Extracellular Space Cell Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix
	Molecular Function	Carboxypeptidase Activity Serine-type Carboxypeptidase Activity Enzyme Activator Activity	Protein Binding Enzyme Binding Protein Domain Specific Binding
	Biological Process	Proteolysis Glycosphingolipid Metabolic Process Intracellular Protein Transport Regulation Of Protein Stability Positive Regulation Of Catalytic Activity Neutrophil Degranulation Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Chaperone-mediated Autophagy	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process
Pathways		Glycosphingolipid metabolism MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation	Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy
Drugs
Diseases		Galactosialidosis	Danon disease; X-linked vacuolar cardiomyopathy and myopathy
GWAS
Interacting Genes		4 interacting genes: GLB1 LAMP2 LMNA NEU1	4 interacting genes: AP4M1 CTSA PIAS4 UCHL1
Entrez ID		5476	3920
HPRD ID		02020	02396
Ensembl ID		ENSG00000064601	ENSG00000005893
Uniprot IDs		B4E324 P10619 X6R5C5 X6R8A1	P13473
PDB IDs		1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT	2MOF 2MOM
Enriched GO Terms of Interacting Partners?
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