NECAB2 and MED14

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
BioGRID (two hybrid)

		NECAB2	MED14
Description		N-terminal EF-hand calcium binding protein 2	mediator complex subunit 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Migraine ( 27322543)
Interacting Genes		63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1	19 interacting genes: ACTN1 ACTN2 AR CTDP1 DCTN1 ESR1 ESR2 HNF4A MED1 MED29 MED9 NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR
Entrez ID		54550	9282
HPRD ID		13263	02172
Ensembl ID		ENSG00000103154	ENSG00000180182
Uniprot IDs		Q7Z6G3	O60244
PDB IDs
Enriched GO Terms of Interacting Partners?
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