MED14 and STAT2

Number of citations of the paper that reports this interaction (PubMedID 12509459)
29

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro, in vivo)

		MED14	STAT2
Description		mediator complex subunit 14	signal transducer and activator of transcription 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Defense Response JAK-STAT Cascade Viral Process Cytokine-mediated Signaling Pathway Regulation Of Cell Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Mitochondrial Fission
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Interleukin-20 family signaling Interferon alpha/beta signaling Regulation of IFNA signaling Regulation of IFNA signaling
Drugs
Diseases
GWAS		Migraine ( 27322543)	Axial length ( 24144296) Height ( 20881960 25429064 23456168) Inflammatory skin disease ( 25574825) Macular thickness ( 30535121) Psoriasis ( 25903422 25574825 23143594 19169254) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624)
Interacting Genes		19 interacting genes: ACTN1 ACTN2 AR CTDP1 DCTN1 ESR1 ESR2 HNF4A MED1 MED29 MED9 NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR	20 interacting genes: AURKA CREBBP CXCR4 DOK4 EGFR EP300 FNTA GAA HDAC1 IFNAR1 IFNAR2 IRF9 IWS1 JAK1 JAK2 MED14 SMARCA4 STAT1 STAT6 TYK2
Entrez ID		9282	6773
HPRD ID		02172	02778
Ensembl ID		ENSG00000180182	ENSG00000170581
Uniprot IDs		O60244	P52630 R9QE65
PDB IDs			2KA4
Enriched GO Terms of Interacting Partners?
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