PRMT7 and DIO3

Number of citations of the paper that reports this interaction (PubMedID 17709427)
56

Data Source:
BioGRID (pull down)

		PRMT7	DIO3
Description		protein arginine methyltransferase 7	iodothyronine deiodinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytosol	Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)	Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Gene Expression By Genetic Imprinting Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation	Thyroid Hormone Generation Biological_process Positive Regulation Of Multicellular Organism Growth Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Negative Regulation Of Eye Photoreceptor Cell Development Retinal Cone Cell Development Oxidation-reduction Process Retinal Cone Cell Apoptotic Process
Pathways		RMTs methylate histone arginines	Regulation of thyroid hormone activity
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 28892062 25673413) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)	Metabolite levels ( 23823483) Pulse pressure ( 30224653) Type 1 diabetes ( 19966805)
Interacting Genes		11 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA POT1 SNRPB ZBTB24	3 interacting genes: APP PRMT5 PRMT7
Entrez ID		54496	1735
HPRD ID		15174	11867
Ensembl ID		ENSG00000132600	ENSG00000197406
Uniprot IDs		A0A024R6Z2 A0A024R726 Q9NVM4	P55073 Q86TU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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