PLXNA1 and RHOD

Number of citations of the paper that reports this interaction (PubMedID 11784792)
51

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		PLXNA1	RHOD
Description		plexin A1	ras homolog family member D
Image		No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Cytoplasm Early Endosome Cytosol Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle
	Molecular Function	Semaphorin Receptor Activity Signaling Receptor Activity	GTPase Activity GTP Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension	Cytokinesis Protein Targeting Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Focal Adhesion Assembly Regulation Of Actin Cytoskeleton Reorganization
Pathways		Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions	Rho GTPase cycle RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Systolic blood pressure ( 31469255) Weight ( 28552196) Whole-brain volume ( 21116278)	Height ( 20881960 25282103)
Interacting Genes		9 interacting genes: AKT1 FES L1CAM NRP1 NRP2 PLXNB1 RHOD RND1 SEMA6D	13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1
Entrez ID		5361	29984
HPRD ID		11868	05776
Ensembl ID		ENSG00000114554	ENSG00000173156
Uniprot IDs		Q9UIW2	E9PIG5 O00212
PDB IDs			2J1L
Enriched GO Terms of Interacting Partners?
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