RHOD and PLXNA1

Number of citations of the paper that reports this interaction (PubMedID 11784792)
51

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RHOD	PLXNA1
Description		ras homolog family member D	plexin A1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Cytosol Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle	Semaphorin Receptor Complex Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Semaphorin Receptor Activity Signaling Receptor Activity
	Biological Process	Cytokinesis Protein Targeting Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Focal Adhesion Assembly Regulation Of Actin Cytoskeleton Reorganization	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension
Pathways		Rho GTPase cycle RHO GTPases Activate Formins	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
Drugs
Diseases
GWAS		Height ( 20881960 25282103)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Systolic blood pressure ( 31469255) Weight ( 28552196) Whole-brain volume ( 21116278)
Interacting Genes		13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	9 interacting genes: AKT1 FES L1CAM NRP1 NRP2 PLXNB1 RHOD RND1 SEMA6D
Entrez ID		29984	5361
HPRD ID		05776	11868
Ensembl ID		ENSG00000173156	ENSG00000114554
Uniprot IDs		E9PIG5 O00212	Q9UIW2
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?
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