PKHD1 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 16243292)
11

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PKHD1	CAMLG
Description		PKHD1 ciliary IPT domain containing fibrocystin/polyductin	calcium modulating ligand
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Cell Cytoplasm Centrosome Cilium Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of External Side Of Plasma Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding
	Biological Process	Kidney Development Cellular Calcium Ion Homeostasis Positive Regulation Of Cell Proliferation Regulation Of Centrosome Duplication Regulation Of TOR Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Homeostatic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cellular Component Movement Negative Regulation Of Protein Kinase B Signaling Cilium Assembly Regulation Of ERK1 And ERK2 Cascade Cell-cell Adhesion	Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			Cyclosporine
Diseases		Polycystic kidney disease
GWAS		Alcohol use disorder ( 30940813) Chronotype ( 30696823) Coffee consumption ( 31046077) Diastolic blood pressure ( 28135244 27841878) Epigenetic age acceleration in alcohol use disorder ( 31466081) Estimated glomerular filtration rate ( 31152163) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998 24002674 29785010 31959993 30054594 29235454) Longevity ( 30294719) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Post bronchodilator FEV1/FVC ratio ( 26634245) Prostate cancer ( 17903305) Red vs. brown/black hair color ( 30531825) Response to fenofibrate (triglyceride levels) ( 27002377) Tea consumption ( 31046077) Urinary sodium excretion ( 31409800) Waist circumference ( 19557197) Weight loss (gastric bypass surgery) ( 23633212)	Height ( 18391951)
Interacting Genes		1 interacting genes: CAMLG	5 interacting genes: EGFR KCNA2 PKHD1 PPIB TNFRSF13B
Entrez ID		5314	819
HPRD ID		05987	03073
Ensembl ID		ENSG00000170927	ENSG00000164615
Uniprot IDs		P08F94	P49069
PDB IDs
Enriched GO Terms of Interacting Partners?
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