ABCB1 and MAPKAP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ABCB1	MAPKAP1
Description		ATP binding cassette subfamily B member 1	MAPK associated protein 1
Image
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome External Side Of Apical Plasma Membrane	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle TORC2 Complex
	Molecular Function	Transporter Activity Protein Binding ATP Binding Xenobiotic Transmembrane Transporting ATPase Activity Efflux Transmembrane Transporter Activity ATPase Activity Ubiquitin Protein Ligase Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Phosphatidylcholine-translocating ATPase Activity Phosphatidylethanolamine-translocating ATPase Activity Ceramide-translocating ATPase Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Ras GTPase Binding Protein Kinase Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Response To Drug Phospholipid Translocation Regulation Of Response To Osmotic Stress Transmembrane Transport Transepithelial Transport Stem Cell Proliferation Ceramide Translocation Export Across Plasma Membrane Positive Regulation Of Anion Channel Activity Drug Transport Across Blood-brain Barrier Regulation Of Chloride Transport	Substantia Nigra Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cellular Response To Oxidative Stress
Pathways		Abacavir transmembrane transport ABC-family proteins mediated transport	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs		ATP Roxithromycin Voacamine Elacridar Tesmilifene FM-VP4 Miltefosine
Diseases
GWAS		Bone mineral density (spine) and age at menarche ( 26312577) Gallbladder cancer ( 28274756) Neurological blood protein biomarker levels ( 31320639)	Body mass index ( 28892062) Diverticular disease ( 30177863) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (calcium channel blockers) ( 31015401) Resting heart rate ( 27798624) Sleep duration ( 30531941) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: BCCIP CAV1 CD4 HAX1 LNX1 MAPKAP1 MAPRE1 NEDD4 PIM1 PSMB8 RNF2	9 interacting genes: ABCB1 AKT1 CDC42EP1 ECI1 MAPK8 NRAS PRKCA SGK1 YWHAG
Entrez ID		5243	79109
HPRD ID		01370	17464
Ensembl ID		ENSG00000085563	ENSG00000119487
Uniprot IDs		A4D1D2 P08183	A0A024R863 Q9BPZ7
PDB IDs		6C0V 6FN1 6FN4 6QEX	3VOQ 5ZCS
Enriched GO Terms of Interacting Partners?
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