PFDN5 and TUBA1B

Number of citations of the paper that reports this interaction (PubMedID 11535601)
8

Data Source:
HPRD (in vivo)

		PFDN5	TUBA1B
Description		prefoldin subunit 5	tubulin alpha 1b
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton	Cytoplasm Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Raft
	Molecular Function	Transcription Corepressor Activity Protein Binding Unfolded Protein Binding	Double-stranded RNA Binding GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division Cellular Response To Interleukin-4
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs			Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		13 interacting genes: BRMS1 CALCOCO2 GLRX3 IKBKG IKZF3 ITSN1 MYC PFDN6 PSME3 TP73 TRIM28 TUBA1B TUBA3C	31 interacting genes: A2M AGTRAP CCT2 EPN2 ESR1 FYN GRM7 GZMM HDAC6 MAPT MINK1 MTCL1 MYC NFKBIA PFDN5 PIK3R1 PSEN1 PTEN PTP4A1 PTPRF PXN SIAH1 SLX1B SMAD2 SNAP91 SRPK2 SUMO2 TERT TMEM253 TOM1L1 TUBG1
Entrez ID		5204	10376
HPRD ID		05359	03960
Ensembl ID		ENSG00000123349	ENSG00000123416
Uniprot IDs		Q99471	P68363
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	2E4H 5IJ0 5IJ9 5N5N 6E7B 6E7C 6I2I 6J4V 6QUS 6QUY 6QVE 6QVJ 6S8L
Enriched GO Terms of Interacting Partners?
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