TUBA1B and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TUBA1B	AGTRAP
Description		tubulin alpha 1b	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Raft	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Double-stranded RNA Binding GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Ubiquitin Protein Ligase Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division Cellular Response To Interleukin-4	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins	Signaling by BRAF and RAF fusions
Drugs		Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS		Bipolar disorder ( 31043756)	Systolic blood pressure ( 19430483)
Interacting Genes		31 interacting genes: A2M AGTRAP CCT2 EPN2 ESR1 FYN GRM7 GZMM HDAC6 MAPT MINK1 MTCL1 MYC NFKBIA PFDN5 PIK3R1 PSEN1 PTEN PTP4A1 PTPRF PXN SIAH1 SLX1B SMAD2 SNAP91 SRPK2 SUMO2 TERT TMEM253 TOM1L1 TUBG1	79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391
Entrez ID		10376	57085
HPRD ID		03960	16379
Ensembl ID		ENSG00000123416	ENSG00000177674
Uniprot IDs		P68363	Q6RW13
PDB IDs		2E4H 5IJ0 5IJ9 5N5N 6E7B 6E7C 6I2I 6J4V 6QUS 6QUY 6QVE 6QVJ 6S8L
Enriched GO Terms of Interacting Partners?
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