PEX1 and PEX6

Number of citations of the paper that reports this interaction (PubMedID 9671729)
30

Data Source:
BioGRID (two hybrid, pull down)
HPRD (in vitro, two hybrid)

		PEX1	PEX6
Description		peroxisomal biogenesis factor 1	peroxisomal biogenesis factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Extracellular Exosome	Photoreceptor Outer Segment Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Photoreceptor Cell Cilium
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity ATPase Activity, Coupled Protein-containing Complex Binding	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity ATPase Activity, Coupled Protein-containing Complex Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Microtubule-based Peroxisome Localization	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization
Pathways		Peroxisomal protein import Peroxisomal protein import	Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Height ( 18391951)	Alzheimer's disease in APOE e4+ carriers ( 25778476)
Interacting Genes		3 interacting genes: PEX26 PEX5 PEX6	8 interacting genes: ATF7IP CERS2 PEX1 PEX26 PEX5 RPL27A RPS14 SMAD3
Entrez ID		5189	5190
HPRD ID		03682	03293
Ensembl ID		ENSG00000127980	ENSG00000124587
Uniprot IDs		A0A0C4DG33 B4DER6 O43933	A0A024RD09 Q13608
PDB IDs
Enriched GO Terms of Interacting Partners?
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