PEX6 and RPS14

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PEX6	RPS14
Description		peroxisomal biogenesis factor 6	ribosomal protein S14
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Photoreceptor Cell Cilium	Nucleoplasm Nucleolus Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity ATPase Activity, Coupled Protein-containing Complex Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Erythrocyte Differentiation Maturation Of SSU-rRNA
Pathways		Peroxisomal protein import Peroxisomal protein import	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		8 interacting genes: ATF7IP CERS2 PEX1 PEX26 PEX5 RPL27A RPS14 SMAD3	8 interacting genes: APP CALM1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33
Entrez ID		5190	6208
HPRD ID		03293	00562
Ensembl ID		ENSG00000124587	ENSG00000164587
Uniprot IDs		A0A024RD09 Q13608	P62263
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?