STK26 and CEP76

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		STK26	CEP76
Description		serine/threonine kinase 26	centrosomal protein 76
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Vesicle Membrane Membrane Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Centrosome Centriole Cytosol Protein-containing Complex
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Cellular Response To Starvation Signal Transduction By Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Response To Hydrogen Peroxide Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Hydrogen Peroxide-induced Cell Death	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking
Pathways		Apoptotic cleavage of cellular proteins	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		12 interacting genes: APP CEP76 GOLGA2 GRB14 IKZF3 MBP NEDD4 PDCD10 RAF1 SRPK1 TRAF6 TRIM27	55 interacting genes: AKAP7 AKT1 BANP C22orf39 CABP5 CAPN3 CCDC92 CCNK CIR1 COIL CRYBA4 CSNK1G1 CUTC DCTD DZIP1L EAF1 EP400P1 FAM90A1 GDAP2 GFAP HSPB7 ILVBL KIAA1143 KIFBP KLHDC4 LATS1 MAGEA11 MBD3 MLH1 NHLRC2 NME5 PAICS PARD6B PIN1 PLCB1 POM121 RADIL RNF128 RPL9 SALL2 SH2D4A SINHCAF STK26 TBC1D27P THRA TOB2 TSPOAP1 TSSC4 TTC21A TUFT1 TXNDC9 WDFY3 ZBTB24 ZMAT2 ZNF85
Entrez ID		51765	79959
HPRD ID		06663	12694
Ensembl ID		ENSG00000134602	ENSG00000101624
Uniprot IDs		Q9P289	B4DP81 Q8TAP6
PDB IDs		3GGF 3W8I 4FZA 4FZD 4FZF 4GEH 5XY9 5YF4
Enriched GO Terms of Interacting Partners?
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