VPS54 and MOGS

		VPS54	MOGS
Description		VPS54 subunit of GARP complex	mannosyl-oligosaccharide glucosidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	GARP Complex Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Syntaxin Binding	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Protein Transport Regulation Of Growth Retrograde Transport, Endosome To Golgi Homeostasis Of Number Of Cells Within A Tissue Musculoskeletal Movement Neurofilament Cytoskeleton Organization	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process
Pathways		Retrograde transport at the Trans-Golgi-Network	Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Clozapine-induced agranulocytosis ( 25187353) Diastolic blood pressure ( 30224653)
Interacting Genes		2 interacting genes: MOGS VPS51	9 interacting genes: C1D CHGB ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54
Entrez ID		51542	7841
HPRD ID		10302	03214
Ensembl ID		ENSG00000143952	ENSG00000115275
Uniprot IDs		Q9P1Q0	A0A384MDR6 Q13724 Q58F09
PDB IDs
Enriched GO Terms of Interacting Partners?
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