MOGS and RAB11FIP5

		MOGS	RAB11FIP5
Description		mannosyl-oligosaccharide glucosidase	RAB11 family interacting protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Membrane Cell Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Centriolar Satellite Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	Protein Binding Rab GTPase Binding Gamma-tubulin Binding
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS			Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Non-word reading ( 30741946) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		9 interacting genes: C1D CHGB ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54	10 interacting genes: ARF6 MOGS NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 RO60 YWHAG
Entrez ID		7841	26056
HPRD ID		03214	16117
Ensembl ID		ENSG00000115275	ENSG00000135631
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	Q9BXF6 Q9UFM0
PDB IDs
Enriched GO Terms of Interacting Partners?
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