EVL and ABI3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EVL	ABI3
Description		Enah/Vasp-like	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium Phagocytic Vesicle	Cytoplasm Membrane Lamellipodium
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Cellular Response To Interferon-gamma Negative Regulation Of Ruffle Assembly	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensity burden ( 25663218)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732)
Interacting Genes		30 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17	36 interacting genes: ABI3BP ACTN3 ARMC7 CEP170P1 CEP44 CYFIP2 DTNB DTNBP1 EIF3H ENAH EVL FARSA FBF1 GRB2 HOMER1 HOMER3 KANK2 KIAA0408 KLC3 KLC4 KRT13 KRT15 MAGEA12 MRFAP1L1 NCK2 NUP58 PAK1 PAK2 PSMA1 RUNX1T1 SNAP23 SOS1 TMEM147 VASP WAS WASF2
Entrez ID		51466	51225
HPRD ID		10942	05900
Ensembl ID		ENSG00000196405	ENSG00000108798
Uniprot IDs		A0A024R6K5 Q9UI08	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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