ZNF593 and ZNRD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ZNF593	ZNRD1
Description		zinc finger protein 593	zinc ribbon domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor	Nucleoplasm RNA Polymerase I Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ribosomal Large Subunit Binding	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Zinc Ion Binding
	Biological Process	Ribosomal Large Subunit Export From Nucleus Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			AIDS progression ( 19115949) Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) HIV-1 control ( 20041166) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		8 interacting genes: GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 RAB1A SRPK2 ZNRD1	17 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 UBE2I ZNF593
Entrez ID		51042	30834
HPRD ID		15866	09601
Ensembl ID		ENSG00000142684	ENSG00000066379
Uniprot IDs		O00488	Q2L6J2 Q9P1U0
PDB IDs		1ZR9
Enriched GO Terms of Interacting Partners?
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