ACOX1 and TYSND1

Number of citations of the paper that reports this interaction (PubMedID 22002062)
16

Data Source:
BioGRID (enzymatic study)

		ACOX1	TYSND1
Description		acyl-CoA oxidase 1	trypsin domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Peroxisome Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Acyl-CoA Oxidase Activity Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding	Protease Binding Serine-type Endopeptidase Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Protein Targeting To Peroxisome Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Lipid Homeostasis	Proteolysis Protein Targeting To Peroxisome Protein Processing Regulation Of Fatty Acid Beta-oxidation
Pathways		Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins TYSND1 cleaves peroxisomal proteins
Drugs		Flavin adenine dinucleotide (3R)-3-HYDROXYDODECANOIC ACID
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS		Body mass index ( 28552196) Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878) Urinary metabolite levels in chronic kidney disease ( 31959995) White matter hyperintensity burden ( 25663218)
Interacting Genes		3 interacting genes: SCP2 SLC2A4 TYSND1	3 interacting genes: ACOX1 OIT3 TH
Entrez ID		51	219743
HPRD ID		02030	15593
Ensembl ID		ENSG00000161533	ENSG00000156521
Uniprot IDs		Q15067	Q2T9J0
PDB IDs
Enriched GO Terms of Interacting Partners?
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