PCBP1 and RALY

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		PCBP1	RALY
Description		poly(rC) binding protein 1	RALY heterogeneous nuclear ribonucleoprotein
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Cholesterol Homeostasis Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Basal cell carcinoma ( 31174203 27539887) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Non-melanoma skin cancer ( 29739929) Red vs. brown/black hair color ( 30531825) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196)
Interacting Genes		42 interacting genes: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 MOGS NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM42 SNRPA SRPK2 SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	11 interacting genes: CELF1 HNRNPC HNRNPD HNRNPH1 HNRNPK KHDRBS1 PCBP1 PIK3CD QKI SPG7 WDR62
Entrez ID		5093	22913
HPRD ID		03128	11480
Ensembl ID		ENSG00000169564	ENSG00000125970
Uniprot IDs		Q15365 Q53SS8	Q53GL6 Q9UKM9
PDB IDs		1WVN 1ZTG 3VKE	1WF1
Enriched GO Terms of Interacting Partners?
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