ATP5F1C and MED15

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	MED15
Description		ATP synthase F1 subunit gamma	mediator complex subunit 15
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane	Nucleoplasm Cytoplasm Membrane Mediator Complex
	Molecular Function	RNA Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Transcription Coregulator Activity Protein Binding
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B PICEATANNOL N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS			Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		25 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CHMP2B DPP3 EGFR ELOF1 FBXO7 GDPD2 ITIH2 MED15 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	12 interacting genes: ATP5F1C ATXN1 CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC
Entrez ID		509	51586
HPRD ID		00156	12117
Ensembl ID		ENSG00000165629	ENSG00000099917
Uniprot IDs		B4DL14 P36542 Q8TAS0	B7Z2H7 G3V1P5 Q6PKB8 Q96RN5
PDB IDs			2GUT
Enriched GO Terms of Interacting Partners?
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