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PAFAH1B1 and PAFAH1B3
Number of citations of the paper that reports this interaction (PubMedID
10727864
)
7
Data Source:
HPRD
(in vitro, two hybrid)
PAFAH1B1
PAFAH1B3
Description
platelet activating factor acetylhydrolase 1b regulatory subunit 1
platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Astral Microtubule
Kinetochore
Cell
Nuclear Envelope
Centrosome
Cytosol
Kinesin Complex
Microtubule Associated Complex
Cytoplasmic Microtubule
Cell Cortex
Cell Leading Edge
Motile Cilium
Nuclear Membrane
Stereocilium
Neuron Projection
Neuronal Cell Body
Synapse
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Central Region Of Growth Cone
Axon Cytoplasm
Cytoplasm
Cytosol
Membrane
Molecular Function
Protein Binding
Microtubule Binding
Heparin Binding
Dynactin Binding
Identical Protein Binding
Phospholipase Binding
Dynein Intermediate Chain Binding
Microtubule Plus-end Binding
Phosphoprotein Binding
Dynein Complex Binding
1-alkyl-2-acetylglycerophosphocholine Esterase Activity
Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
Platelet-activating Factor Acetyltransferase Activity
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
Microtubule Cytoskeleton Organization
Ameboidal-type Cell Migration
Acrosome Assembly
Neuron Migration
Positive Regulation Of Cytokine-mediated Signaling Pathway
Microtubule-based Process
Nuclear Migration
Chemical Synaptic Transmission
Germ Cell Development
Neuroblast Proliferation
Learning Or Memory
Retrograde Axonal Transport
Adult Locomotory Behavior
Protein Secretion
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Neuron Projection Development
Lipid Catabolic Process
Stem Cell Division
Transmission Of Nerve Impulse
Corpus Callosum Morphogenesis
Hippocampus Development
Layer Formation In Cerebral Cortex
Cerebral Cortex Neuron Differentiation
Cerebral Cortex Development
Actin Cytoskeleton Organization
Microtubule Organizing Center Organization
Osteoclast Development
Positive Regulation Of Embryonic Development
Establishment Of Planar Polarity Of Embryonic Epithelium
Regulation Of GTPase Activity
Cortical Microtubule Organization
Positive Regulation Of Axon Extension
Positive Regulation Of Mitotic Cell Cycle
Negative Regulation Of JNK Cascade
Platelet Activating Factor Metabolic Process
Vesicle Transport Along Microtubule
Brain Morphogenesis
Neuromuscular Process Controlling Balance
Microtubule Sliding
Nuclear Envelope Disassembly
Establishment Of Centrosome Localization
Maintenance Of Centrosome Location
Auditory Receptor Cell Development
Positive Regulation Of Dendritic Spine Morphogenesis
Regulation Of Microtubule Cytoskeleton Organization
Cochlea Development
Microtubule Cytoskeleton Organization Involved In Establishment Of Planar Polarity
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Microtubule Motor Activity
Lipid Metabolic Process
Spermatogenesis
Nervous System Development
Brain Development
Lipid Catabolic Process
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
COPI-independent Golgi-to-ER retrograde traffic
Drugs
(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Adverse response to drug (
30420678
)
Neurociticism (
29500382
)
Neuroticism (
27089181
)
Self-reported tiredness (
28194004
)
Interacting Genes
22 interacting genes:
CLIP1
CSNK2A1
DAB1
DCTN1
DCTN2
DCX
DNAI1
FBXO7
HSPH1
KARS1
KATNA1
KATNB1
MAP1B
MAP2
NDE1
NDEL1
NUDC
PAFAH1B2
PAFAH1B3
PDE4D
TNIK
TUBA1A
33 interacting genes:
BRD7
CCDC90B
CHMP7
COPS6
CRMP1
DDX24
ECH1
EEF1A1
ERG28
GAPDH
GBP2
GDF9
HSPH1
IGSF21
LNX1
LRIF1
MED31
PAFAH1B1
PAFAH1B2
PLEKHM1
RBM48
SDCBP2
SETDB1
SUMO4
TERF1
TERF2IP
TLE1
TP53
TUBB2A
UNC119
XRCC6
ZBTB16
ZHX1
Entrez ID
5048
5050
HPRD ID
03329
04354
Ensembl ID
ENSG00000007168
ENSG00000079462
Uniprot IDs
P43034
A0A024R0L6
Q15102
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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